Tyrimai ir naudota literatūra

Chihara, G., Hamuro, J., Maeda, Y., Arai, Y., and Fukuoka, F. Antitumor Polysaccharide Derived Chemically from Natural Glucan (Pachyman). Nature, 225: 943-944, 1970.
Ikekawa, T., Uehara, N., Maeda, Y., Nakanishi, M., and Fukuoka, F. Antitumour Activity of Aqueous Extracts of Some Edible Mushrooms. Cancer Res., 29: 734-735, 1969.
Borchers A T, Stern J S, Hackman, R M, Keen, C L and Gershwin E (1999) Mushrooms, tumours and immunity. Proceedings of the Society of Experimental Biology and Medicine 221, 28I-293.
Chihara G (1992) Immunopharmacology of Lentinan, a polysaccharide isolated from Lentinus edodes: its application as a host defence potentiator. International Journal of Oriental Medicine 17, 67-77.
Fisher M and Yang L X (2002) Anticancer effects and mechanisms of polysaccharide-K (PSK): implications of cancer immunotherapy. Anticancer Research 22, l7 37 -L7 54.
Hobbs C R (2000) Medicinal value of Lentinus edodes. International Journal of Medicinal Mushrooms, 287-302.Arora O (1986) Mushrooms Demystified. Ten Speed Press, Berkeley, CA 94707.
Bohn J A and BeMillar J N (1995) (1-3,B-D-glucans as biological response modifiers: a review of structure- functional activity relationships. Carbohydrate Polymers 28, 3-14.
Belkin, M., Hardy, W. G., Perrault, A., and Sato, H. Swelling and Vacuolization Induced in Ascites Tumor Cells by Polysaccharides from Higher Plants. Cancer Res., 19: 1051-1061, 1959.
Chihara, G., Maeda, Y., Hamuro, G., Sasaki, T., and Fukuoka, F. Inhibition of Mouse Sarcoma 180 by Polysaccharides from Lentinus edodes (Berk.) Sing. Nature, 222; 687-688, 1969.
Diller, I. C., Fisher, N. E., and Gable, D. Effect of Glucan on Mouse Sarcoma 37. Proc. Soc. Exptl. Biol. Med., 117: 107-110, 1964.
Kamasuka, T., Momoki, Y., and Sakai, S. Antitumor Activity of Polysaccharide Fractions Prepared from Some Strains of Basidiomycetes. Gann, 59: 443-445, 1968.Komatsu, N., Okubo, S.,
Kikumoto, S., Kimura, K., Saito, G., and Sakai, S. Host-mediated Antitumor Action of Schizophyllan, a Glucan Produced by Schizophyllum commune. Gann, 60:137-144,1969.Nakahara, W.,
Fukuoka, F., Maeda, Y., and Aoki, K. The Hostmediated Antitumor Effect of Some Plant Polysaccharides. Gann, 283-288, 1964.
Nakayoshi, H. Studies on Antitumor Activity of Polysaccharide Produced by a Strain of Crepidotus sp. II. Antitumor Action. Nippon Saikingaku Zasshi, 23: 7-12, 1968.
Sakai, S., Takeda, S., Kamasuka, T., Momoki, Y., and Sugayama, J. Antitumor Action of Some Glucans; Especially on Its Correlation to Their Chemical Structure. Gann, 59: 507-511, 1968.
Shibata, S., Nishikawa, Y., Takeda, T., and Tanaka, M. Polysaccha rides in Lichen and Fungi. I. Antitumor Active Polysaccharides of Gyophora esculenta Miyoshi and Lasallia papulosa (Ach.) Llano.Chem. Pharm. Bull. (Tokyo), 16: 2362-2369, 1968.
Srivastava, H. C., Breuninger, E., Creech, H. J., and Adams, G. A. Preparation and Properties of Polysaccharide-Lipid Complexes from Serratia marcescens. Can. J. Biochem. Physiol., 40:905-918, 1962.
Staub, A. M. Removal of Proteins: Sevag Method. In: R. L. Whistler (ed.), Methods in Carbohydrate Chemistry, Vol. 5, pp. 5-6. New York: Academic Press, Inc., 1965.Adachi Y, Ishii I Ikeda I Hoshimo A, Tamura H, Aketagawa d Tanaka S and Ohno N (2004). Characterisation of beta-glucan recognition site on C-type lectin, dectin 1. Infection and Immunity 72, 4t59-4t7r.

Bertozzi C R and Kiessling L L (2001) Chemical glycobiology. Science 291, 23257 -2364.

Hong F, Yan J, Baran J T Allendorf D J, Hansen R D, Ostroff G R, Xing P X, Cheung NK and Ross G D (2004) Mechanism by which orally administered beta-glucans enhance the umoricidal activity of antitumour monoclonal antibodies in murine tumour models. Journal of Immunology L73,797-806.

Katan M B and De Roos N M (2003) Public health: toward evidence-based health claims for functionaI foods . Science 299, 206-207.

Kidd P M (2000) The use of mushroom glucans and proteoglycans in cancer therapy. Alternatiue Medicine Reuiews 5, 4-27.

Kodama N, Murata Y, Asakawa A, Innui A, Hayashi M, Sakai N and Nanba H (2005). Maitake D-fraction enhances antitumour effects and reduces immunosuppression by mitomycin-C in tumourbearing mice. Nutrition 21, 624-629.

Mizuno T (1999) The extraction and development of antitumour-active polysaccharides from medicinal mushrooms in Japan. International Journal of Medicinal Mushrooms t, 9-29.

Ohno N (2005). Structural diversity and physiological functions of B glucans. International Journal of Medicinal Mushrooms 7 , L67 -t73.

Reshetnikov S V Wasser S P and Tan K K (2001) Higher Basidiomycetes as a source of antitumour and immunostimulating polysaccharides (review). Intrernational Journal of Medicinal Mushrooms 3,36L-394.

Rowan N J, Smith J E and Sullivan R (2003) Immunomodulatory activities of mushroom glucans and polysaccharide-protein complexes in animals and humans (Review). International Journal of Medicinal Mushroorns 5,95-110.

Samorini G (2001) New data from the ethnomycology of psychoactive mushrooms. International Journal of Medicinal Mushoroms 3,257 -278.

Stamets P (2000) Growing Gourmet and Medicinal Mushoroms. Ten Speed Press, Berkeley, CA 94707.

Sugiyama Y, Sajis and Kunied a (200D. Efficacy of anticancer biotherapy with PSK. Biotherapy L6, 10-16.

Sullivan R, Smith J E and Rowan lt J (2006) Medicinal mushrooms and cancer therapy: translating a traditional practice into Western medicine. Perspectiues in Biology and Medicine (in press).

Sun ZY,Yang Q Y and Fei H L (1999) The ameliorative effect of PSP on the toxic and side reactions of chemo- and radio-therapy of cancers. In: Aduanced Research in PSP 1999, ed. Yang Quing- Yao. The Hong Kong Association for Health CareLtd., Hong Kong, China, pp. 304-307.

Tomochika H, Gouchi A, Okanobu K, Sasaki A, Fuchimoto S and Orita K (1989) The effect and distribution of a protein-bound polysaccharide preparation, PSK (Krestin) intratumorally injected prior to surgery into gastric cancer patients. Acta Med. Okayama 43,289-297.

Tzianabos O T (2000) Polysaccharide immunomodu-Iators as therapeutic agents: structural aspectsand biological function. Clinical MicrobiologyReviews 13, 523-533.

Wasser S P (2002) Medicinal mushrooms as a source of antitumour and immunomodulating polysaccharide s. Applied Microbiology and Biotechnology 60,258-274.

Wasser SP (2005). Shiiitake (Lentinus edodes). Encyclopaedia of Dietary Supplements, Marcel Dekker, pp. 653-664.

Willard T (1990) Reishi ntushroorn: herb of spiritual potency and medical wonder. Sylvan Press, Washington.

Ying J Z, Mao X L, Ma W M,Zong Y C and Wen H A (1987) Icons of Medicinal Fungi from China (Transl. Xu YH), Science Press, Beijing. Zaidman B-Z, Yassin H, Makajna J and Wasser S P (2005). Medicinal mushroom modulators of molecular targets and cancer therapeutics Applied Microbiology and Biotechnology 67 , 453-468.

Bensky, D. and Gamble, A. 1993. Chinese Materia Medica. 2nd Ed., Eastland Press, Seattle.

Breene, W. 1990. Nutritional and medicinal value of speciality mushrooms. Journal of Food Production 53, 883-894.

Carter, J. 1993. Food: Your Miracle Medicine. Harper Collins Publishers Inc., New York.

Chang, S.T. 1991. Cultivated mushrooms. In: Handbook of Applied Mycology, Vol. 3., pp. 221-240.Marcel Dekker, New York.

Chang, S.T. and Buswell, J.A. 1996. Mushroom nutriceuticals. World Journal of Microbial Biotechnology 12, 473-476.

Hobbs, C. 1995. Medicinal Mushrooms: An Exploitation of Tradition, Healing and Culture. Botanica Press, Santa Cruz.

Jong, S.C., Birmingham, J.M. and Pai, S.H. 1991. Immunomodulatory substances of fungal origin. Journal of Immunology and Immunopharmacology 115-122.

Mizuno, T., Sakai, T. and Chihara, G. 1995. Health foods and medicinal usage of mushrooms. Food Review International 11, 69-81.

Sadler, M. and Saltmarsh, M. (eds.) 1998. Functional Foods: The Consumer, the Products and the Evidence. Royal Society of Chemistry, Cambridge.

Saris, W.H.M., Asp, N.G.L. et al. 1998. Functional food science and substrate metabolism. British Journal of Nutrition 80, Suppl. 547-75.

Steinmetz, K.A. and Potter, J.D. 1991. Vegetables, fruit and cancer. 1. Epidemiology. Cancer Causes and Control 2, 325-357.

Thomas, P.R. and Earl, R. (eds). 1994. Enhancing the food supply. In: Opportunities in Nutrition and Food Science. Washington DC, National Academy Press, pp. 98-142.

Zeisel, S. 1999. Regulation of “Nutraceuticals”. Science 285, 1853-1866.

Ikekawa, T. 2001. Beneficial effects of edible and medicinal mushrooms on health care. International Journal of Medicinal Mushrooms 3, 291-298.

Ikekawa, T., Saitoh, H., Feng, W., Zhang, H., Li, L. and Matsuzawa, T. 1992. Antitumour activity of Hypsizygus marmoreus. 1. Antitumour activity of extracts and polysaccharides. Chemical and Pharmaceutical Bulletin 40, 1954-1957.

Ikekawa, T., Saitoh, H., Feng, W., Zhang, H., Li, L. and Matsuzawa, T. 1992b. Preventive effects of Hypsizygus marmoreus51st Anniversary Meeting of the Japanese Society for Cancer Research. Abstract.

Kurashiga, S., Akuzawa, Y. and Endo, F. 1997. Effects of Lentinus edodesGrifola frondosa and Pleurotus ostreatus administration in cancer outbreaks and activities of macrophages and lymphocytes in mice treated with a carcinogen, N-butyl-N-butamolinitrosoamine. Immunopharmacology and Immunotoxicology 19, 175-183.

Hobbs, Ch. Medicinal Mushrooms: An Exploration of Tradition, Healing, and Culture, 2nd Ed.; Botanica Press, Inc.: Santa Cruz, CA, USA, 1995.

Miles, P.G.; Chang, S.T. Mushroom Biology: Concise Basics and Current Development; World Scientific: Singapore, 1997; 193.

Przbylowicz, P.; Donoghue, J. Shiitake Grower’s Handbook: The Art and Science of Mushroom Cultivation; Hunt Publ. Co.: Dubugue, Kendall, 1990; 199.

Chang, S.T. World production of cultivated edible and medicinal mushrooms in 1997 with emphasis on Lentinus edodes (Berk.) Sing. In China. Int. J. Med. Mushr. 1999, 1, 387–409.

Royse, D. Specialty mushrooms and their cultivation. Horticult. Rev. 1997, 19, 59–97.

Wasser, S.P.; Weis, A.L. Medicinal Mushrooms. Lentinus edodes (Berk.) Singer; Nevo, E., Ed.; Peledfus Publ. House: Haifa, Israel, 1997; 95.

Mizuno, T. Shiitake, Lentinus edodes: functional properties for medicinal and food purposes. Food Rev. Int. 1995, 11, 7–21.

Hobbs, Ch. Medicinal value of Lentinus edodes (Berk.) Sing. A literature review. Int. J. Med. Mushr. 2000, 2, 287–302.

Earle, F.S. The genera of the North American gill-fungi. Bull. N. Y. Bot. Gard. 1909, 5, 373–451.

Murrill, W.A. Additions to Florida fungi. 1. Bull. Torrey Bot. Club 1939, 66, 29–37.

Mizuno, T. A development of antitumor polysaccharides from mushroom fungi. Food Food Ingred. J. Jpn. 1996, 167, 69–85.

Wasser, S.P. Medicinal mushrooms as a source of antitumor and immunomodulating polysaccharides. Appl. Microbiol. Biotechnol. 2002, 60, 258–274.

Smith, J.; Rowan, N.; Sullivan, R. Medicinal mushrooms. Their therapeutic properties and current medical usage with special emphasis on cancer treatment; Special Report Commissioned by Cancer research UK. The University of Strathclyde in Glasgow, 2002; 256.

Yap, A.T.; Ng, M.L. Immunopotentiating properties of lentinan (1-3)-b-D-glucan extracted from culinary-medicinal shiitake mushroom Lentinus edodes (Berk.) Singer Agaricomycetideae). Int. J. Med. Mushr. 2003, 5, 352–372.

Chihara, G.; Maeda, Y.Y.; Hamuro, J.; Sasaki, T.; Fukuoka, F. Inhibition of mouse Sarcoma 180 by polysaccharides from Lentinus edodes (Berk.). Sing. Nature 1969, 222, 687–688.

Chihara, G.; Hamuro, J.; Maeda, Y.Y.; Arai, Y.; Fukuoka, F. Antitumor polysaccharide derived chemically from natural glucan (pachyman). Nature (London) 1970, 225, 943–944.

Chihara, G.; Hamuro, J.; Maeda, Y.Y.; Arai, Y.;Fukuoka, F. Fractionation and purification of the polysaccharides with marked antitumor activity, especially lentinan, from Lentinus edodes (Berk.) Sing. (an edible mushroom). Cancer Res. 1970, 30, 2776–2781.

Chihara, G.; Hamuro, J.; Maeda, Y.Y.; Shiio, T.; Suga, T.; Takasuka, N.; Sasaki, T. Antitumor and metastasis-inhibitory activities of lentinan as an immuno-modulator: an overview. Cancer Detect. Rev. Supp. 1987, 1, 423–443.

Yap, A.T.; Ng, M.L. An improved method for the isolation of lentinan from the edible and medicinal shiitake mushroom, Lentinus edodes (Berk.) Sing. (Agaricomycetideae). Int. J. Med. Mushr. 2001, 3, 9–20.

Moriyama, M. et al. Anti-tumor effect of polysaccharide lentinan on transplanted ascites hepatoma-134 in C3H/He mice. In Manipulation of Host Defence Mechanisms, International Congress Series 576; Excerpta Media: Amsterdam, 1981.

Mori, K.; Toyomasu, T.; Nanba, H.; Kuroda, H. Antitumor activity of fruit bodies of edible mushrooms orally administrated to mice. Mushr. J. Trop. 1987, 7, 121–126.

DeVere White, R.W.; Hackman, R.M.; Soares, S.E.; Beckett, L.A.; Sun, B. Effect of a mushroom mycelium extract on the treatment of prostate cancer. Urology 2002, 60, 640–644.

Ngai, P.H.K.; Ng, T.B. Lentin, a novel and potent antifungal protein from shiitake mushroom with inhibitory effects on activity of human immunodeficiency virus-1 reverse transcriptase and proliferation of leukemia cells. Life Sci. 2003, 73, 3363–3374.

Fujii, T.; Maeda, H.; Suzuki, K.; Ishida, N. Isolation and characterization of a new antitumor polysaccharide, KS-2, extracted from culture mycelia of Lentinus edodes. J. Antibiot. 1978, 31, 1079–1090.

Suzuki, C. Killing activity of experimental tumor cells given to macrophage by new antitumor immunopotentiator, KS-2. Japan J. Bacter. 1978, 33, 78–85.

Kurashige, S.; Akusawa, Y.; Endo, F. Effects of Lentinus edodes, Grifola frondosa, and Pleurotus ostreatus administration on cancer outbreak, and activities of macrophages and lymphocytes in mice treated with a carcinogen, N-butyl-Nbutanolnitrosoamine. Immunopharm. Immunotoxicol. 1997, 19, 175–183.

Ladanyi, A.; Timar, J.; Lapis, K. Effect of lentinan on macrophage cytotoxicity against metastatic tumour cells. J. Cancer Immunol. Immunother. 1993, 36, 123–126.

Yoshino, S.; Tabata, T.; Hazama, S.; Iizuka, N.; Yamamoto, K.; Hirayama, M.; Tangoku, A.; Oka, M. Immunoregulatory effects of the anitumour polysaccharide lentinan on Th1=Th2 balance in patients with digestive cancers. Anticancer Res. 2000, 20, 4707–4711.

Aoki, T. Lentinan. In Immune, Modulation Agents and Their Mechanisms; Fenichel, R.L., Chirgis, M.A., Eds.; Immunol Studies, 1984; 25, 62–77.

Wasser, S.P.; Weis, A.L. Medicinal properties of substances occurring in higher Basidiomycetes mushrooms: current perspectives (review). Int. J. Med. Mushr. 1999, 1, 31–62.

Yang, B.K.; Kim, D.H.; Jeong, S.Ch.; Das, S.; Choi, Y.S.; Shin, J.S.; Lee, S.Ch.; Song, Ch.H. Hypoglycemic effect of a Lentinus edodes exopolymer produced from a submerged mycelial culture. Biosci. Biotechnol. Biochem. 2002, 66, 937–942.

Amagase, H. Treatment of hepatitis B patients with Lentinus edodes mycelium. Proceedings of the XII International Congress of Gastroenterology, Lisbon; 1987, 197.

Suay, I.; Arenal, F.; Asensio, F.J.; Basilio, A.; Cabello, M.A.; Diez, M.T.; Garcia, J.B.; del Val, A.G.; Corrochategui, J.; Hernandez, P.; Pelaez, F.; Vicente, M.F. Screening of asidiomycetes for antimicrobial activities. Antonie van Leeuwenhoek 2000, 78, 129–139.

Tochikura, T.S. et al. Inhibition (in vitro) of replication and of the cytopathic effect of human immunodeficiency virus by an extract of the culture medium of Lentinus edodes mycelia. Med. Microbiol. Immunol. 1988, 177, 235–244.

Sarkar, S. et al. Antiviral effect of the extract of culture medium of Lentinus edodes mycelia on the replication of herpes simplex virus type 1. Antiviral Res. 1993, 20, 293–303.

Taguchi, T. et al. Clinical trials on lentinan (polysaccharide). In Immunomodulation by Microbial Products and Related Synthetic Compounds; Yamamura, Y. et al., Ed.; Elsevier Science: New York, 1982; 467–475.

Taguchi, T. et al. Clinical efficacy of lentinan on patients with stomach cancer: end point results of a four-year follow-up survey. Cancer Detect. Prev. 1987, 1, 333–349.

Oka, M. et al. Immunological analysis and clinical effects of intra-abdominal and intrapleural injection of lentinan for malignant ascites and pleural effusion. Biotherapy 1992, 5, 107–112.

Ueda, A. et al. Allergic contact dermatitis in shiitake (Lentinus edodes (Berk.) Sing.) growers. Contact Dermatitis 1992, 26, 228–233.

Van Leon, P.C. Mushroom worker’s lung. Detection of antibodies against Shii-take (Lentinus edodes) spore antigens in Shii-take workers. J. Occup. Med. 1992, 34, 1097–1101.

Yang, Q.Y.; Jong, S.C. Medicinal mushrooms in China. Mushr. Sci. XII. 1989, 631–642.

Jong, S.C.; Birmingham, J.M. Medicinal and therapeutic value of the shiitake mushroom. Appl. Microbiol., 30:53-184, 1993.Komemushi, S.; Yamamoto, Y.; Fujita, T. Antimicrobial substance produced by Lentinus edodesJ. Antibact. Antifung. Agents., 23:81-86, 1995.

Komemushi, S.; Yamamoto, Y.; Fujita, T. Purification and identification of antimicrobial substances produced by Lentinus edodesJ. Antibact. Antifung. Agents., 24:21-25, 1996.

Mizuno, T.; Hagiwara, T.; Nakamura, T.; Ito, H.; Shimura, K.; Sumiya, T.; Asakura, A. Antitumor activity and some properties of watersoluble polysaccharides from “Himematsutake”, the fruiting of Agaricus blazei Murill. Agric. Biol. Chem., 54:2889-2896, 1990.

Mizuno, T. Bioactive biomolecules of mushrooms: food function and medicinal effect of mushroom fungi. Food Rev. Int., 11:7-21, 1995.

Mizuno, T.; Morimoto, M.; Minato. K.I.; Tsuchida, H. Polisaccharides from Agaricus blazei stimulate lymphocytes T-cell subsets in mice. Biosci. Biotechnol. Biochem., 62:434-437, 1998.

Osaki, Y.; Kato, T.; Yamamoto, K.; Okubo, J.; Miyazaki, T. Antimutagenic and bactericidal substances in the fruit body of a Basidiomycete Agaricus blazeiBiol. Abstr., 98:342-350, 1994.

Pontecorvo, G.; Roper, J.A.; Hemmons, L.M.; McDonald, K.D.; Bufton, A.W.J. The genetics of Aspergillus nidulansAdv. Genet.5:141-238, 1953.

Sasaki, S.H.; Linhares, R.E.C.; Nozawa, C.M.; Montalván, R.; Paccola-Meirelles, L.D. Strains of Lentinula edodes suppress growth of phytopathogenic fungi and inhibit Alagoas serotype of vesicular stomatitis virus. Braz. J. Microbiol., 32:52-55, 2001.

Sterner, O.; Bergman, R.; Kesler, E.; Magnusson, G.; Nilsson, L.; Wickberg, B.; Zimerson, E.; Zetterberg, G. Mutagens in larger fungi. I. Forty-eight species screened for mutagenic activity in the Salmonella/microsome assay. Mutat. Res., 101:269-281, 1982.

Sugiyama, K.; Akachi, T.; Yamakawa, A. The hypocholesterolemic action of Lentinus edodes is evoked through alteration of phospholipid composition of liver microsomes in rats. Biosci. Biotechnol. Biochem., 31:1983-1985, 1995.

Suzuki, H.; Hyama, K.; Yoshida, O.; Yamazaki, S.; Yamamoto, N.; Toda, S. Structural characterization of the immunoactive and antiviral water-solubilized lignin in an extract of the culture medium of Lentinus edodes mycelia (LEM). Agric. Biol. Chem., 54:479-487, 1990.

Suzuki, M.; Iwashiro, M.; Takatsuki, F.; Kuribayashi, K.; Hamuro, J. Reconstitution of antitumor effects of lentinan in nude mice: roles of delayes-types hypersensitivity reaction triggered by CD4-positive T cell clone in the infiltration of effector cells into tumor. JPN. J. Cancer Res., 85:409-417, 1994.

Suzuki, M.; Takatsuki, F.; Maeda, Y.Y.; Hamuro, J.; Chihara, G. Antitumor and immunological activity of lentinan in comparison with LPS. Int. J. Immunopharmacol., 16:463-468, 1994.

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